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English to Portuguese: Mammographic Performance in a Population-based Screening Program: Before, during, and after the Transition from Screen-Film to Full-Field Digital Mammography General field: Medical Detailed field: Medical (general)
Source text - English Purpose: To compare performance measures before, during, and after the transition from screen-film mammography (SFM) to full-field digital mammography (FFDM) in a population based screening program.
Materials and Methods: No institutional review board approval was required for this analysis involving anonymized data for women aged 50–69 years enrolled in the Norwegian Breast Cancer Screening Program during 1996–2010. The χ² test was used to examine the equality of proportions of recall rates, positive predictive value of recall examinations and of invasive procedures, in addition to rates of screening-detected and interval cancers in women initially screened with SFM and FFDM and for women subsequently screened with SFM after SFM, FFDM after SFM, and FFDM after FFDM.
Results: The recall rate was 3.4% (47 091 of 1 391 188) for SFM and 2.9% (13 130 of 446 172) for FFDM (P < .001). The biopsy rate was 1.4% (19 776 of 1 391 188) for SFM and 1.1% (5108 of 446 172) for FFDM (P < .001). The rate of screening detected ductal carcinoma in situ was higher (P = .019) while the rate of invasive breast cancer was lower (P < .001) for FFDM compared with those for SFM. The rate of both invasive screening-detected and interval breast cancer remained stable during the transition from SFM to FFDM (when the previous examination was SFM) and after FFDM was firmly established (when the previous examination was FFDM, > 25 months after FFDM adoption) (P < .05). The positive predictive value of recall examinations and of invasive procedures increased from 19.3% (4559 of 23 598) and 48.3% (4651 of 9623) to 22.7% (681 of 2995) and 57.5% (689 of 1198), respectively, after adoption of FFDM (P < .001).
Conclusion: After the initial transitional phase from SFM to FFDM, population-based screening with FFDM is associated with less harm because of lower recall and biopsy rates and higher positive predictive values after biopsy than screening with SFM.
Translation - Portuguese Objetivo: comparar as medidas de desempenho antes, durante e, depois da transição da mamografia convencional em tela-filme (SFM) à mamografia digital de campo total (FFDM) em um programa de rastreio de base populacional.
Materiais e métodos: não houve necessidade de uma aprovação do conselho de revisão institucional para esta análise envolvendo dados anônimos para mulheres com idade entre 50 – 69 anos inscritas no Programa Norueguês de Rastreio de Câncer de Mama entre 1996 – 2010. O teste χ² foi usado para examinar a igualdade de proporções de taxas de reconvocação, o valor preditivo positivo de exames de reconvocação e de procedimentos invasivos, além de examinar taxas de canceres detectados em rastreios e canceres desenvolvidos entre os rastreios em mulheres inicialmente rastreadas com SFM e FFDM, e para mulheres que posteriormente foram rastreadas com SFM após SFM, FFDM após SFM e FFDM após FFDM.
Resultados: a taxa de reconvocação foi de 3,4% (47.091 de 1.391.188) para SFM e 2,9% (13.130 de 446.172) para FFDM (P < .001). A taxa de biópsia foi de 1,4% (19.776 de 1.391.188) para SFM e 1,1% (5.108 de 446.172) para FFDM (P < .001). A taxa de carcinoma ductal in situ detectado no rastreio foi maior (P = .019) enquanto a taxa de câncer de mama invasivo foi menor (P < .001) para FFDM comparado com as taxas de SFM. As taxas, tanto de câncer de mama invasivo detectado no rastreio, quanto de câncer de mama detectado no intervalo entre duas triagens permaneceram estáveis durante a transição do SFM para FFDM (quando o exame anterior foi SFM) e após FFDM ter sido firmemente estabelecida (quando o exame anterior era FFDM, > 25 meses após a adoção de FFDM) (P < .05). O valor positivo preditivo de exames de reconvocação e de procedimentos invasivos aumentou de 19,3% (4.559 de 23.598) para 22,7% (681 de 2.995), e de 48,3% (4.651 de 9.623) para 57,5% (689 de 1.198), respectivamente, após a adoção de FFDM (P < .001).
Conclusões: após a fase inicial de transição de SFM para FFDM, o rastreio de base populacional com FFDM está associado com menos danos por causa de baixas taxas de reconvocação e de biópsia, e os valores preditivos positivos após biópsia maior do que o rastreio com SFM.
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Years of experience: 10. Registered at ProZ.com: Dec 2015.
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Freelance translator and English teacher, nearly graduated in Biological Sciences but quit to apply for Med School. I am a fast learner, always willing to seek more knowledge in order to achieve my clients objectives.
Keywords: portuguese, english, hebrew, spanish, medical, biomedicine, biology, history, religion, music. See more.portuguese, english, hebrew, spanish, medical, biomedicine, biology, history, religion, music, tourism, entertainment, public relations, art, travel. See less.
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