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Polish translation: (utrzymanie odpowiedniego) poziomu nukleofilów

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)

English term or phrase:	nucleophilic tone
Polish translation:	(utrzymanie odpowiedniego) poziomu nukleofilów
Entered by:	Pawel Bartoszewicz

13:10 Nov 8, 2016

English to Polish translations [PRO]
Medical - Medical (general)

English term or phrase: nucleophilic tone

We propose that both oxidant and antioxidant signaling are main features of redox homeostasis. As the redox shift is rapidly reversed by feedback reactions, homeostasis is maintained by continuous signaling for production and elimination of electrophiles and nucleophiles. Redox homeostasis, which is the maintenance of nucleophilic tone, accounts for a healthy physiological steady state. Electrophiles and nucleophiles are not intrinsically harmful or protective, and redox homeostasis is an essential feature of both the response to challenges and subsequent feedback.

Nonetheless, feedback control of the NF-κB pathway results in reestablishment of nucleophilic tone. Oxidants produced by the NF-κB activated pro-inflammatory pathway increase Nrf2 activity, which in turn increases nucleophilic tone. This feedback loop is continuously active and responsible for much of redox homeostasis. Too long or too much of an upturn of NF-κB activity will cause the production of more electrophiles than can be handled by cellular homeostatic system.

Pawel Bartoszewicz KudoZ activity Questions: 821 (1 open) (1 without valid answers) (16 closed without grading) Answers: 531 Poland
Local time: 05:51

(utrzymaniem opodowiedniego) poziomu nukleofilów

Explanation:
Paweł nie mam odnośnika polskiego, tone to również poziom, nukleofile wiadomo, czas Ci się pewnie kończy. Jeśli nie masz niczego lepszego, to ja bym tak to przetłumaczył, poprzedzając 'homeostazą redukcji redoks " - jak to zauważył geopiet.

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Note added at 2 days7 hrs (2016-11-10 20:30:21 GMT)
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reakcji redoks - nie redukcji. Ze zmęczenia już padam :) Przepraszam.

Selected response from:

Marcin Pustkowski
Poland

Grading comment

Bardzo dziękuję za pomoc i dyskusję!
4 KudoZ points were awarded for this answer

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(utrzymaniem opodowiedniego) poziomu nukleofilów

Marcin Pustkowski

Discussion entries: 7

Answers

2 days 7 hrs confidence:

(utrzymaniem opodowiedniego) poziomu nukleofilów

Marcin Pustkowski
Poland
Works in field
Native speaker of:

Polish
PRO pts in category: 1376

Grading comment

Bardzo dziękuję za pomoc i dyskusję!

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