deleted cancer

Russian translation: см.

06:19 May 18, 2023
English to Russian translations [PRO]
Medical - Medical (general)
English term or phrase: deleted cancer
SMARCA4 is frequently mutated in primary tumors (i.e., deleted or inactivated), particularly in lung cancer (12%), melanoma, liver cancer and pancreatic cancer.

SMARCA2 is one of the top essential genes in SMARCA4-mutant (deleted) cancer cell line.

Сancer is SMARCA4 deleted cancer
Palladium
United States
Local time: 06:07
Russian translation:см.
Explanation:
Рак представляет собой рак, полученный/развившийся в результате делеции гена SMARCA4.
Selected response from:

Igor Andreev
Local time: 06:07
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
3см.
Igor Andreev
Summary of reference entries provided
different parsing
liz askew

  

Answers


4 days   confidence: Answerer confidence 3/5Answerer confidence 3/5
см.


Explanation:
Рак представляет собой рак, полученный/развившийся в результате делеции гена SMARCA4.

Igor Andreev
Local time: 06:07
Native speaker of: Native in RussianRussian
PRO pts in category: 806
Login to enter a peer comment (or grade)




Reference comments


1 day 8 hrs peer agreement (net): +1
Reference: different parsing

Reference information:
https://preludetx.com › uploads › 2021/04 › S...
PDF
****deletion of SMARCA4-mutant cancer cell line****. from preludetx.com
nonsense, frameshift deletion, splice site mutations) and SMARCA4-deleted cancer cells are highly dependent on its paralog gene SMARCA2 for their survival.

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Note added at 1 jour 8 heures (2023-05-19 14:53:19 GMT)
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https://meridian.allenpress.com › aplm › article › SMAR...
9 Apr 2020 — The ****SMARCA4 mutations/deletions****, best investigated in NSCLC cell lines, predominantly involve the bromodomain, resulting in a truncated BRG1 ...

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Note added at 1 jour 8 heures (2023-05-19 14:57:38 GMT)
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https://www.proz.com/personal-glossaries/entry/35213285-gene...

liz askew
United Kingdom
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 4

Peer comments on this reference comment (and responses from the reference poster)
agree  Igor Andreev
2 days 19 hrs
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